Association Between the Development of Thrombosis and Worsening of Disease Severity in Patients With Moderate COVID-19 on Admission – From the CLOT-COVID StudyMulticenter Study Published on 2023-02-242023-07-09 Journal: Circulation journal : official journal of the Japanese Circulation Society [Category] COVID19(2023년), [키워드] COVID-19 D-dimer thrombosis Worsening of the severity. [DOI] 10.1253/circj.CJ-22-0252 PMC 바로가기 [Article Type] Multicenter Study
Systemic Markers in Ophthalmic Manifestations of Post Corona Virus Disease-19 (COVID-19)Article Published on 2023-02-012023-07-08 Journal: Ocular immunology and inflammation [Category] COVID19(2023년), [키워드] COVID-19 D-dimer Ophthalmic manifestations Serum ferritin sight threatening manifestations. Systemic markers [DOI] 10.1080/09273948.2021.2025253 PMC 바로가기
COVID-19 and the injured patient: A multicenter reviewResearch article Published on 2022-12-012022-10-05 Journal: The Journal of surgical research [Category] 바이오마커, [키워드] adverse events Affect age Analysis baseline characteristics C-reactive protein Coagulopathy Cohort collected Comorbidities composed Coronavirus disease 2019 COVID-19 cumulative D-dimer demographics diabetes events ferritin Frame Hospitalization hypertension In-hospital death Injury ISS Kaplan–Meier method log-rank test median morbidity and mortality Mortality multicenter neurologic New York Older outcome outcomes Patient patients performed physiological Primary outcome Result Retrospective analysis severity shown study period surgical tested trauma trauma patient trauma patients were excluded were used [DOI] 10.1016/j.jss.2022.06.068 [Article Type] Research article
Low BALF CD4 T cells count is associated with extubation failure and mortality in critically ill covid-19 pneumonia낮은 BALF CD4 T 세포 수는 중환자의 covid-19 폐렴에서 발관 실패 및 사망률과 관련이 있습니다Article Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 바이오마커, 진단, [키워드] affected alveolar alveolar macrophage analysed average BALF BALF CD4 T-cells count baseline Biomarker bivariate analysis Bronchoalveolar lavage fluid caspase caspase-3 cause CD4 CD4 T cell CD4 T-cell Characteristics clinical Clinical characteristics conducted COVID-19 COVID-19 patients COVID-19 pneumonia COVID-19 pneumonia patient COVID-19 pneumonia patients Critically ill critically ill COVID-19 patients Critically ill COVID-19 pneumonia D-dimer D-dimer level eight enrolled extubation failure. groups help IL-17 IL-6 immunopathology IMPROVE Indonesia intubation Invasive mechanical ventilation Laboratory lung Macrophage material Mortality no significant difference no significant differences outcome Patient performed Pneumonia profile Referral reported right lung severe pneumonia severity significant differences significantly survived T-cells Tertiary Tregs understanding was performed were measured [DOI] 10.1080/07853890.2022.2095012 PMC 바로가기 [Article Type] Article
IgG-RBD Response Due to Inactivated SARS-CoV-2 Vaccine: Alteration in D-Dimer and Fibrinogen Concentrations, Association with Comorbidities and Adverse EffectsArticle Published on 2022-11-032022-11-15 Journal: Laboratory medicine [Category] SARS, 진단, [키워드] Adverse alteration appear blood sample both groups changes in Concentration CoronaVac Coronavirus infection COVID-19 COVID-19 infection D-dimer D-dimer level domain Effect effective fibrinogen fibrinogen level first vaccination IgG Immunoglobulin individual infected individual Infection Mask Measures Participants Protective response Safe SARS-CoV-2 second dose second vaccination Side effects significantly higher statistically subject vaccination vaccination. Vaccine was obtained were measured [DOI] 10.1093/labmed/lmac047 PMC 바로가기
Serum neurofilament light chain levels in Covid-19 patients without major neurological manifestationsArticle Published on 2022-11-012022-11-15 Journal: Journal of Neurology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] absence Admission baseline Biomarker Blood Brescia C-reactive protein change controls correlated COVID-19 CRP D-dimer disease severity evaluated Evidence excluded explained fibrinogen healthy controls Hospital stay Hospitalized hypoxic Increased longitudinal measure Neuroaxonal damage neurofilament Neurofilament light chain (NFL) neurological manifestation neurological manifestations neurotoxic PaO2/FiO2 ratio parameters Patient patients plasma promote reported respiratory respiratory impairment SARS-CoV-2 scale serum serum creatinine serum CRP Serum level serum sample serum. significantly Simoa systemic inflammation Variation were measured White blood cell with mild disease [DOI] 10.1007/s00415-022-11233-5 PMC 바로가기
Clinical, laboratory and immunohistochemical characterization of in situ pulmonary arterial thrombosis in fatal COVID-19Article Published on 2022-11-012022-11-15 Journal: Thrombosis research [Category] SARS, 바이오마커, [키워드] Admission age Artery characterized clinical Coagulopathy composed contribute controls coronavirus COVID-19 COVID-19 patient Critical disease D-dimer died disease disease severity elevations eosin evaluated Evidence fatal COVID-19 FEU Hypoxemia ICU immunohistochemistry in both groups Inflammation Inflammatory IQR Laboratory laboratory feature LDH lung main role marker neutrophil organ damage parenchymal damage Patient Platelet Pneumonia pneumonia case post-mortem lung pulmonary thrombi selected serum significantly higher thrombosis thrombosis. transfer WBC White blood cell [DOI] 10.1016/j.thromres.2022.09.012 PMC 바로가기
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trialsArticle Published on 2022-11-012022-11-15 Journal: European Journal of Clinical Pharmacology [Category] SARS, 치료제, [키워드] 95% CI 95% confidence interval addition anti-inflammatory effect antiparasitic antiviral activity blinded clinical benefit continuous variable COVID-19 D-dimer D-dimer level death dichotomous variable Disease progression Effect effect size Efficacy and safety element eligibility enrolled Evidence Frequency ICU admission in vitro individual Inflammation Invasive mechanical ventilation lactate dehydrogenase LDH magnitude Meta-analysis Mild moderate Moderate COVID-19 nitazoxanide no difference Patient patients peer-reviewed performed Placebo placebo-controlled positive positive RT-PCR Primary outcome randomized clinical trial RCT RCTs receiving reducing reduction in reported risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infection. secondary outcome serum biomarker SMD standardized mean difference systematic review tested to define treat treated Viral load WBC were used White blood cell with COVID-19 [DOI] 10.1007/s00228-022-03380-5 PMC 바로가기
Association of Interleukin-17F Polymorphism and Mortality Predictors with the Risk of COVID-19Article Published on 2022-10-272022-11-15 Journal: International journal of clinical practice [Category] 변종, 진단, [키워드] age allele Analysis association AUC case-control study CD4 cells Characteristics control subject controls Coronavirus disease-19 COVID-19 COVID-19 infection COVID-19 mortality COVID-19 patient COVID-19 patients cutoff point D-dimer death determine enzyme-linked immunosorbent exhibiting expression Genotype genotyping healthy higher odd hypertension IL-17 immunological injuries in-hospital mortality independent predictor investigated Laboratory no significant difference non-survivor outcome participant polymorphism predictor proinflammatory risk of COVID-19 ROC Curve subset suggested survivor susceptibility T lymphocytes tested variant WBC White blood cell with COVID-19 [DOI] 10.1155/2022/4761631 PMC 바로가기
Saliva metabolomic profile of COVID-19 patients associates with disease severityArticle Published on 2022-10-222022-11-15 Journal: Metabolomics [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] 5-aminolevulinic acid Asymptomatic Biomarker Biomarkers C-reactive protein cellular change changes changes in Comparisons controls Coronavirus disease 2019 correlated COVID-19 COVID-19 group COVID-19 patient COVID-19 patients D-dimer diagnostic Disease progression disease severity dysregulation early stage expected Infection intensity Level liquid liquid chromatography-mass spectrometry metabolite metabolomic metabolomics Mild moderate molecular non-infected non-severe patients parameter Patient physiological plasma positively correlated profile prognostic prognostic biomarker risk Saliva Saliva. SARS-CoV-2 screened severity significantly sphingosine stages utility were used [DOI] 10.1007/s11306-022-01936-1 PMC 바로가기